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Cheng-Fang Tsai 

Cheng-Fang Tsai (蔡政芳) Associate Professor

Education
Ph. D., in Food Science and Technology, National Taiwan University, Taiwan
TEL
+886-4-23323456 ext.1866
Lab
I418
Research Areas
Chinese herbal medicine, Microbiology, Biochemistry, Biotechnology, Molecular Biology, Biomedical materials
Research Field
Nanotechnology and Biomedical Material, Biochemistry, Food microbiology, Medical Microorganism, Biochemistry Lab
Journal Papers
  • The linker domain of a Piromyces rhizinflata endoglucanase stabilizes the protein expressed in E.coli. Enzyme and Microbial Technology. , ENZYME AND MICROBIAL TECHNOLOGY ,SCI 蔡政芳(Cheng-Fang Tsai) 2001 , 28(7-8):582-589
  • A comparative analysis of two cDNA clones of the cellulase gene family from anaerobic fungus Piromyces rhizinflata. , ANAEROBE ,SCI 蔡政芳(Cheng-Fang Tsai) 2003 , 9():131-140
  • Preparation and characterization of water-soluble chitosan produced by Maillard reaction. , FISHERIES SCIENCE ,SCI 蔡政芳(Cheng-Fang Tsai) 2006 , 72():1096-1103
  • Antioxidant Properties and Antioxidant Compounds of Various Extracts from the Edible Basidiomycete Grifola Frondosa (Maitake) , MOLECULES ,SCI 蔡政芳(Cheng-Fang Tsai) 2011 Apr, 16():3197-3211
  • Ghrelin induces cell migration through GHS-R, CaMKII, AMPK and NF-kappaB signaling pathway in glioma cells , JOURNAL OF CELLULAR BIOCHEMISTRY ,SCI 蔡政芳(Cheng-Fang Tsai), 盧大宇(Dah-Yuu Lu) 2011 May, 112(10):2931-2941
  • Antibacterial characteristics and activity of water-soluble chitosan derivatives prepared by the Maillard Reaction. , MOLECULES ,SCI 蔡政芳(Cheng-Fang Tsai) 2011 Oct, 16():8504-8514
  • A Comparative study of the second-order hydrophobic moments for globular proteins: The consensus scale of hydrophobicity and the CHARMM Partial atomic charges. , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ,SCI 蔡政芳(Cheng-Fang Tsai) 2011 Nov, 12():8449-8465
  • Berberine induces heme oxygenase-1 up-regulation through phosphatidylinositol 3-kinase/AKT and NF-E2-related factor-2 signaling pathway in astrocytes , INTERNATIONAL IMMUNOPHARMACOLOGY ,SCI 蔡政芳(Cheng-Fang Tsai) 2012 Jan, 12(1):94-100
  • Wogonin Induces Reactive Oxygen Species Production and Cell Apoptosis in Human Glioma Cancer Cells , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ,SCI 蔡政芳(Cheng-Fang Tsai) 2012 Apr, 13():9877-9892 [link]
  • Interaction of inflammatory and anti-inflammatory responses in microglia by Staphylococcus aureus-derived lipoteichoic acid ,TOXICOLOGY AND APPLIED PHARMACOLOGY ,SCI Bor-Ren Huan(Bor-Ren Huang)、蔡政芳(Cheng-Fang Tsai)、Hsiao-Yun Li(Hsiao-Yun Lin)、Wen-Pei Tsen(Wen-Pei Tseng)、Shiang-Suo H(Shiang-Suo Huang)、Chi-Rei Wu(Chi-Rei Wu)、Chingju Lin(Chingju Lin)、Wei-Lan Yeh(Wei-Lan Yeh)、Dah-Yuu Lu(Dah-Yuu Lu) 2013 Mar,269():43-50 [link]
  • Growth inhibition and antioxidative status induced by selenium-enriched broccoli extract and selenocompounds in DNA mismatch repair-deficient human colon cancer cells , FOOD CHEMISTRY ,SCI 蔡政芳(Cheng-Fang Tsai)、Bor-Rung Ou、Yu-Chuan Lia(Yu-Chuan Liang)、葉貞吟(Jan-Ying Yeh)* 2013 Mar, 139():267-273 [link]
  • Interaction of inflammatory and anti-inflammatory responses in microglia by Staphylococcus aureus-derived lipoteichoic acid , TOXICOLOGY AND APPLIED PHARMACOLOGY ,SCI Bor-Ren Huang(Bor-Ren Huang), 蔡政芳(Cheng-Fang Tsai), Hsiao-Yun Lin(Hsiao-Yun Lin), Wen-Pei Tseng(Wen-Pei Tseng), Shiang-Suo Huang(Shiang-Suo Huang), Chi-Rei Wu(Chi-Rei Wu), Chingju Lin(Chingju Lin), Wei-Lan Yeh(Wei-Lan Yeh), Dah-Yuu Lu(Dah-Yuu Lu) 2013 Mar, 269():43-50
  • Glial cell line-derived neurotrophic factor induces cell migration in human oral squamous cell carcinoma , ORAL ONCOLOGY ,SCI 蔡政芳(Cheng-Fang Tsai) 2013 Aug, 49():1103-1112
  • Anti-Neuroinflammatory Effects of the Calcium Channel Blocker Nicardipine on Microglial Cells: Implications for Neuroprotection , PLoS One ,SCI 蔡政芳(Cheng-Fang Tsai) 2014 Mar, 9(3):e91167-e91167
  • Osthole Suppresses the Migratory Ability of Human Glioblastoma Multiforme Cells via Inhibition of Focal Adhesion Kinase-Mediated Matrix Metalloproteinase-13 Expression , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ,SCI 蔡政芳(Cheng-Fang Tsai) 2014 Mar, 15():3889-3903
  • Exogenous endothelin-1 induces cell migration and matrix metalloproteinase expression in U251 human glioblastoma multiforme , JOURNAL OF NEURO-ONCOLOGY ,SCI 蔡政芳(Cheng-Fang Tsai) 2014 Apr, 118(2):257-269
  • p53 Is a Key Regulator for Osthole-Triggered Cancer Pathogenesis , JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY ,SCI Ssu-Ming Huang(Ssu-Ming Huang), 蔡政芳(Cheng-Fang Tsai), Dar-Ren Chen(Dar-Ren Chen), Min-Ying Wang(Min-Ying Wang), Wei-Lan Yeh(Wei-Lan Yeh) 2014 Jun, 2014():ID 175247,-1-9 page
  • Regulatory Effects of Fisetin on Microglial Activation , MOLECULES ,SCI 蔡政芳(Cheng-Fang Tsai) 2014 Jun, 19():8820-8839
  • Regulatory Effects of Caffeic Acid Phenethyl Ester on Neuroinflammation in Microglial Cells , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ,SCI 蔡政芳(Cheng-Fang Tsai) 2015 Mar, 16():5572-5589
  • Naringenin Suppresses Neuroinflammatory Responses through Inducing Suppressor of Cytokine Signaling 3 Expression , MOLECULAR NEUROBIOLOGY ,SCI 蔡政芳(Cheng-Fang Tsai) 2016 Mar, 53(2):1080-1091
  • Cobalt Protoporphyrin Upregulates Cyclooxygenase-2 Expression Through a Heme Oxygenase-Independent Mechanism. , MOLECULAR NEUROBIOLOGY ,SCI Lin HY(Lin HY), 蔡政芳(Cheng-Fang Tsai) 2016 Sep, 53():4497-4508
  • Interlukin-18 Is a Pivot Regulatory Factor on Matrix Metalloproteinase-13 Expression and Brain Astrocytic Migration. , MOLECULAR NEUROBIOLOGY ,SCI Chen JH(Chen JH), 蔡政芳(Cheng-Fang Tsai) 2016 Nov, 53():6218-6227
  • Peri-foci adipose-derived stem cells promote chemoresistance in breast cancer , Stem Cell Research & Therapy ,SCI Wei-Lan Yeh(Wei-Lan Yeh), 蔡政芳(Cheng-Fang Tsai), Dar-Ren Chen(Dar-Ren Chen) 2017 Jul, 8():177-188
  • Inhibition of estrogen receptor reduces connexin 43 expression in breast , TOXICOLOGY AND APPLIED PHARMACOLOGY ,SCI 蔡政芳(Cheng-Fang Tsai), Yu-Kai Cheng(Yu-Kai Cheng), Dah-Yuu Lu(Dah-Yuu Lu), Shu-Lin Wang(Shu-Lin Wang), Chen-Ni Chang(Chen-Ni Chang), 張培均(Pei-Chun Chang), Wei-Lan Yeh(Wei-Lan Yeh) 2017 Dec, 338():182-190
Conference Papers
  • Antibacterial activity of water soluble chitosan derivatives prepared by Maillard reaction. 2007幾丁質幾丁聚醣年會暨研討會 萬能科大學桃園, 2007.5 ~ 2007.5 蔡政芳
  • Antibacterial effects of water soluble chitosan derivatives against Staphylococcus aureus and Escherichia coli. 2008幾丁質幾丁聚醣研討會, 台南, 台灣。2008/05. 成功大學, 2008.5 ~ 2008.5 蔡政芳、李錦楓
  • Antioxidant activity of the Taiwan Folk Medicine Ixeris laevigata var. oldhami. 第二屆中國醫藥大學暨亞洲大學生物科技研討會 中國醫藥大學, 2009.3.16 ~ 2009.3.16 蔡政芳
  • Antioxidant properties of the extracts from Grifola frondosa. 第二屆中國醫藥大學暨亞洲大學生物科技研討會 中國醫藥大學, 2009.3.16 ~ 2009.3.16 蔡政芳
  • Antioxidant properties of the extracts from Grifola frondosa varieties BT-5 第三屆亞洲大學暨中國醫藥大學生物科技研討會 亞洲大學, 2010.3.16 ~ 2010.3.16 蔡政芳
  • Novel nanoparticles for anti-cancer drug delivery system. 第三屆亞洲大學暨中國醫藥大學生物科技研討會 亞洲大學, 2010.3.16 ~ 2010.3.16 蔡政芳
  • Studies on antioxidative activity and antioxidant components of methanolic extracts from Ixeris laevigata. 第三屆亞洲大學暨中國醫藥大學生物科技研討會 亞洲大學, 2010.3.16 ~ 2010.3.16 蔡政芳
  • Coupling Effects of Amino Acids in T-cell Epitope Prediction. The 4th Asian Young Researchers Conference on Computational and Omics Biology 新加坡, 2010.12.1 ~ 2010.12.1 蔡政芳
  • Choquet Integral Algorithm for T-cell Epitope Prediction Based on Fuzzy Measure.The 8th International Conference on Fuzzy Systems and Knowledge Discovery上海, 2011.7.26 ~ 2011.7.26蔡政芳
  • Adipokines induce cell migration in brain tumor
  • Preparation of novel nanoparticles and their applications on the encapsulation of Grifola frondosa extracts
  • Characterization of nanoparticles with low molecular weight chitosan for oral Doxorubicin delivery
  • Doxorubicin-incorporated nanoparticles composed of chitosan and antitumor activity against MCF-7 cells in vitro 台灣食品科學技術學會第43次會員大會 東海大學, 2013.11.29 ~ 2013.11.29 蕭凱文、李維元、吳馨柔、蔡政芳
  • Characterization of two homologous cellulase genes from anaerobic fungus Piromyces rhizinflata: Cloning, expression and molecular structures 台灣食品科學技術學會第43次會員大會 東海大學, 2013.11.29 ~ 2013.11.29 蔡政芳、吳馨柔、李維元、張培均
  • Osthole Suppresses the Migratory Ability of Human Brain Tumor International Institute of Chemical, Biological & Environmental Engineering Bali, Indonesia., 2014.2.6 ~ 2014.2.7 Dah-Yuu Lu、蔡政芳、Wei-Lan Yeh
  • Caffeic Acid as A Neuroinflammatiory Inhibitor with Antioxidant Properties in Microglial Activation 第二十九屆生物醫學聯合學術年會 台北, 2014.3.15 ~ 2014.3.16 盧政昆、蔡政芳
  • Doxorubicin-incorporated nanoparticles composed of chitosan and antitumor activity against MCF-7 cells in vitro 第七屆中國醫藥大學暨亞洲大學生物科技研討會 中國醫藥大學, 2014.5.14 ~ 2014.5.14 蕭凱文、李維元、吳馨柔、蔡政芳
  • Cloning and expression of two homologous cellulase genes from anaerobic fungus Piromyces rhizinflata: Homology modeling, structural comparison and characterization 第七屆中國醫藥大學暨亞洲大學生物科技研討會 中國醫藥大學, 2014.5.14 ~ 2014.5.14 蔡政芳、吳馨柔、李維元、張培均
  • Neuroprotective effect of the calcium channel blocker nicardipine onmicroglial cells. Molecular & Cellular Neurobiology: Exploring the Frontiers of Foundational and Translational Neuroscience Molecular & Cellular Neurobiology: Exploring the Frontiers of Foundational and Translational Neuroscience. Gordon Research Seminar/The Hong Kong University of Science and Technology, Hong Kong, 2014.6 ~ 2014.6
  • Mining the potential compounds of lowering cholesterol from natural products. 第八屆亞洲大學暨中國醫藥大學生物科技暨食品安全研討會 台中, 2015.3.17 ~ 2015.3.17 范剛紳、蔡政芳、張培均
  • Molecular dynamics studies of the TCM compounds for inhibition of in-stent restenosis in coronary atherosclerosis 第八屆亞洲大學暨中國醫藥大學生物科技暨食品安全研討會 台中, 2015.3.17 ~ 2015.3.17 郭家珍、蔡政芳、張培均、許承瑜、蔡進發
  • Regulatory Effects of Fisetin on Microglial Activation 103 學年度研發日暨中亞聯大兩校合作學術研討會 台中, 2015.4.2 ~ 2015.4.2 、張培均、蔡政芳
  • Naringenin Suppresses Neuroinflammatory Responses Through Inducing Suppressor of Cytokine Signaling 3 Expression 103學年度研發日暨中亞聯大兩校合作學術研討會 台中, 2015.4.2 ~ 2015.4.2 、蔡政芳、張培均
Books
  • 蔡政芳(Cheng-Fang Tsai), Antibacterial effects of water soluble chitosan derivatives against Staphylococcus aureus and Escherichia coli., 2008.5
  • 蔡政芳(Cheng-Fang Tsai), Antibacterial activity of water soluble chitosan derivatives prepared by Maillard reaction., TSIA and International SEMATECH, 2007
Book Chapters
  • 蔡政芳(Cheng-Fang Tsai), Antibacterial activity of water soluble chitosan derivatives prepared by Maillard reaction., TSIA and International SEMATECH, 2007.
  • 蔡政芳(Cheng-Fang Tsai), Antibacterial effects of water soluble chitosan derivatives against Staphylococcus aureus and Escherichia coli., , 2008.5
  • 蔡政芳(Cheng-Fang Tsai), 2011 亞洲大學與中國醫藥大學兩校合作學術研討會論文集 Adipokines induce cell migration in brain tumor , 2011.11
Patents
  • Polynucleotides encoding cellulase enzymes from Piromyces rhizinflaata, US 6222028, 2001 ~ 2015
  • A DNA sequence coding for an exo - cellobiohydrolase with cellulase, xylanase and -glucanase activities, US 6428996, 2002 ~ 2016
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